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Genomic sequencing in congenital heart disease (CHD) patients often discovers novel genetic variants, which are classified as variants of uncertain significance (VUS). Functional analysis of each VUS is required in specialised laboratories, to determine whether the VUS is disease causative or not, leading to lengthy diagnostic delays.
Childhood obesity and physical inactivity are two of the most significant modifiable risk factors for the prevention of non-communicable diseases. Yet, a third of children in Wales and Australia are overweight or obese, and only 20% of UK and Australian children are sufficiently active.
WHO, as requested by its member states, launched the Expanded Programme on Immunization (EPI) in 1974 to make life-saving vaccines available to all globally. To mark the 50-year anniversary of EPI, we sought to quantify the public health impact of vaccination globally since the programme's inception.
This study identified alignment of indicators across different initiatives and data collection instruments as a foundation for future harmonization of adolescent health measurement.
Neonatal sepsis remains one of the key challenges of neonatal medicine, and together with preterm birth, causes almost 50% of all deaths globally for children younger than 5 years. Compared with advances achieved for other serious neonatal and early childhood conditions globally, progress in reducing neonatal sepsis has been much slower, especially in low-resource settings that have the highest burden of neonatal sepsis morbidity and mortality.
Eight outstanding researchers from The Kids Research Institute Australia and the Institute-led Broome STEM Festival are finalists in the 2025 Premier’s Science Awards.
Researchers from The Kids Research Institute Australia have contributed to a landmark study revealing climate change will have a detrimental impact on one of the greatest threats to the health of children in the Global south – diarrhoea.
The Kids Research Institute Australia has been awarded a prestigious National Health and Medical Research Council (NHMRC) tender to lead the national review of the revised Draft Statement on Consumer and Community Involvement in Health and Medical Research.
The health of the world’s 1.96 billion adolescents is at a critical tipping point.
Dr Kefyalew Alene, who heads the Geospatial and Tuberculosis team at The Kids and is a senior research fellow within the Curtin School of Population Health, has used cutting edge technology to transform the way TB transmission is predicted, understood and managed globally.