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Risk factors for group A streptococcal pharyngitis and skin infections: A case control studyGroup A streptococcal (GAS) infections can trigger an immune-mediated response resulting in acute rheumatic fever. The role of social and environmental risk factors for GAS pharyngitis and skin infections are not well understood.
Research
Rheumatic heart disease in The Gambia: clinical and valvular aspects at presentation and evolution under penicillin prophylaxisRheumatic heart disease (RHD) remains the leading cause of cardiac-related deaths and disability in children and young adults worldwide. In The Gambia, the RHD burden is thought to be high although no data are available and no control programme is yet implemented. We conducted a pilot study to generate baseline data on the clinical and valvular characteristics of RHD patients at first presentation, adherence to penicillin prophylaxis and the evolution of lesions over time.
Research
Benzathine penicillin G for the management of RHD: Concerns about quality and access, and opportunities for intervention and improvementBenzathine penicillin G is an important antibiotic for the treatment and prevention of group A streptococcal infections associated with rheumatic fever and...
Research
Attendances during the First 12 Months of Life for Aboriginal Children in Five Remote Communities of Northern AustraliaThe median number of presentations per child in the first year of life was 21 with multiple reasons for presentation.
News & Events
Co-ordinated approach urgently required to slow progression of antibiotic resistanceAboriginal mum and child
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$2 million grant to develop diagnostic tool for rheumatic feverThe Kids Research Institute Australia & Menzies School of Health Research will lead an international project to develop a diagnostic tool for acute rheumatic fever.
Research
Acceptability of sonicated versus unsonicated reconstituted (powdered) benzathine penicillin G for rheumatic fever prophylaxisJonathan Carapetis AM AM MBBS FRACP FAFPHM PhD FAHMS Executive Director; Co-Head, Strep A Translation; Co-Founder of REACH 08 6319 1000 contact@
Research
Defining target penicillin concentrations for subsequent studies of a reformulated long-acting benzathine penicillin prototypeJonathan Tim Carapetis AM Barnett AM MBBS FRACP FAFPHM PhD FAHMS PhD Executive Director; Co-Head, Strep A Translation; Co-Founder of REACH Head,
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Molecular Detection of Scabies by PCR Using a Next Generation Sequencing (NGS) ApproachAsha Bowen BA MBBS DCH FRACP PhD GAICD FAHMS OAM Head, Healthy Skin and ARF Prevention Head, Healthy Skin and ARF Prevention Areas of expertise: Skin
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Pharmacokinetics of intramuscular versus subcutaneous administration of Benzathine Penicillin GJonathan Rosemary Carapetis AM Wyber AM MBBS FRACP FAFPHM PhD FAHMS MBChB MPH FRACGP PhD Executive Director; Co-Head, Strep A Translation; Co-Founder