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MYCN sensitizes neuroblastoma to the MDM2-p53 antagonists Nutlin-3 and MI-63We hypothesized that reactivation of p53 by inhibition of its negative regulator will result in p53-mediated growth arrest and apoptosis.
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Tertiary paediatric refugee health clinic in Western Australia: Analysis of the first 1026 childrenThe aim of this study is to describe the epidemiology of common conditions in resettled paediatric refugees attending a tertiary multidisciplinary RHC.
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Late-talking and risk for behavioural and emotional problems during childhood and adolescenceAlthough many toddlers with expressive vocabulary delay ("late talkers") present with age-appropriate language skills by the time they are of school age...
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Breastfeeding and early child development: A prospective cohort studyBreastfeeding has been associated with multiple developmental advantages for the infant; however, there have also been a number of studies that find...
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MEIS proteins as partners of the TLX1/HOX11 oncoproteinAberrant expression of the TLX1/HOX11 proto-oncogene is associated with a significant subset of T-cell acute lymphoblastic leukemias...
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Awareness and impact of the ‘Bubblewrap’ advertising campaign among Aboriginal smokers in Western AustraliaAntismoking mass media campaigns have been shown to reduce smoking prevalence in the mainstream community.
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Antifungal therapy in infants and children with proven, probable or suspected invasive fungal infectionsThis review aims to systematically identify and summarise the effects of different antifungal therapies in children with proven, probable or suspected...
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Early immunological influences on asthma development: opportunities for early interventionEarly immunological influences on asthma development: opportunities for early intervention
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Increased longevity and the comorbidities associated with intellectual and developmental disabilityThe contributors, all world experts in their fields, also discuss what we can learn from the presence of co-morbidities.
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Airway narrowing assessed by anatomical optical coherence tomography in vitro: dynamic airway wall morphology and functionPrevious histological and imaging studies have shown the presence of variability in the degree of bronchoconstriction of airways sampled at different locations.