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Research

A molecular dynamics study of C1r and C1s dimers: Implications for the structure of the C1 complex

Complement is an important part of the immune system. It is initiated through three different pathways known as the classical, lectin, and alternative pathway.

Research

Multiple sclerosis: A disease of affluence?

Multiple sclerosis is rare in tropical areas, but quite common in developed countries.

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The potential impact of smoke-free facilities on smoking cessation in people with mental illness

The aim of this paper was to estimate the degree to which smoke-free facilities may facilitate smoking cessation in smokers with mental illness by estimating...

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Family functioning in families with a child with Down syndrome: A mixed methods approach

This study aimed to explore the factors that predict functioning in families with a child with Down syndrome using a mixed methods design.

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Associations between anxious-depressed symptoms and cardiovascular risk factors in a longitudinal childhood study

The objective of the study was to examine the influence of anxious/depressed scores on cardiovascular risk factors throughout childhood.

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Exposure to professional pest control treatments and the risk of childhood acute lymphoblastic leukemia

Previous studies suggest that exposure to pesticides increases the risk of childhood acute lymphoblastic leukemia

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Changes in thymic regulatory T-cell maturation from birth to puberty: Differences in atopic children

We report vaccine efficacy against CIN3+ and adenocarcinoma in situ (AIS) in the end-of-study analysis of PATRICIA (PApilloma TRIal against Cancer In young...

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Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

Blood pressure is a heritable trait influenced by several biological pathways and responsive to environmental...

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The dual-pathway and cognitive-behavioural models of binge eating: prospective evaluation and comparison

The aim of this study was to evaluate and compare the dual-pathway, original cognitive-behavioural, and enhanced "transdiagnostic" cognitive-behavioural...