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Research

Changes in cell morphology guide identification of tubulin as the off-target for protein kinase inhibitors

Early changes in cell morphology upon treatments are a strong indication that the inhibitor is directly targeting tubulin

Research

Proximity to Liquor Stores and Adolescent Alcohol Intake: A Prospective Study

Liquor store availability in early adolescence may be a risk factor for alcohol intake in early and middle, but not late, adolescence

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Ultraviolet irradiation of skin alters the faecal microbiome independently of vitamin D in mice

Skin exposure to ultraviolet radiation alters the faecal microbiome, and further investigations to explore the implications of this in health and disease are warranted

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Does the Risk Outweigh the Benefits? Adolescent Responses to Completing Health Surveys

Self-reported experiences of adolescents in population-based samples when completing health-related surveys on topics with varying potential for evoking distres

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Discovering the sense of touch: Protocol for a randomised controlled trial examining the efficacy of a intervention for children with cerebral palsy

This study will assess the efficacy of an intervention to increase somatosensory discrimination ability in children with cerebral palsy

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RT Prepare: a radiation therapist-delivered intervention reduces psychological distress in women with breast cancer referred for radiotherapy

The RT Prepare intervention was effective in reducing breast cancer patients’ psychological distress and preparing patients for treatment

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A platform for discovery of functional cell-penetrating peptides for efficient multi-cargo intracellular delivery

This report thus establishes a discovery platform for identifying novel, functional CPPs to expand the delivery landscape of druggable intracellular targets for biological therapeutics

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Autistic-like traits in childhood predict later age at menarche in girls

We investigated the relationship between autistic-like traits in early childhood and age at menarche in typically developing girls.

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Early detection of lung function abnormalities in young children with cystic fibrosis

In this review, we have examined the role of lung function testing in infants and preschool children with CF.

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Airway Epithelial Cells Condition Dendritic Cells to Express Multiple Immune Surveillance Genes

AEC-conditioned DC showed selective upregulation of chemokines that recruit Th1 cells, but minimal change in chemokines linked to Th2 cell recruitment.