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Maternal Serum Vitamin D Levels During Pregnancy and Offspring Neurocognitive DevelopmentNew research links poor language to lack of Vitamin D in womb.
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Vitamin D and atopy and asthma phenotypes in childrenThe purpose of this Review was to give an overview of the recent research into whether a lack of vitamin D contributes to the development of atopy and asthma...
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Th2-polarisation of cellular immune memory to neonatal pertussis vaccinationCurrent infant vaccination against pertussis in North America and Australia requires three doses of vaccines including diphtheria, tetanus and acellular...
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Whole‐cell pertussis vaccine in early infancy for the prevention of allergy in childrenAtopic diseases are the most common chronic conditions of childhood. The apparent rise in food anaphylaxis in young children over the past three decades is of particular concern, owing to the lack of proven prevention strategies other than the timely introduction of peanut and egg.
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Enhanced Neutralizing Antibody Responses to Rhinovirus C and Age-Dependent Patterns of InfectionRhinovirus (RV) C can cause asymptomatic infection and respiratory illnesses ranging from the common cold to severe wheezing. The aim was to identify how age and other individual-level factors are associated with susceptibility to RV-C illnesses. Longitudinal data from the COAST (Childhood Origins of Asthma) birth cohort study were analyzed to determine relationships between age and RV-C infections. Neutralizing antibodies specific for RV-A and RV-C (three types each) were determined using a novel PCR-based assay.
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Functional differences in airway dendritic cells determine susceptibility to IgE-sensitizationRespiratory IgE-sensitization to innocuous antigens increases the risk for developing diseases such as allergic asthma.
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Developmental regulation of type 1 and type 3 interferon production and risk for infant infections and asthma developmentType 1 and 3 interferon response capacity appears strongly developmentally constrained at birth
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Basophil counts in PBMC populations during childhood acute wheeze/asthma are associated with future exacerbationsOur findings suggest that the proportion of degranulated basophils can also be associated with recurrent exacerbations
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A marked shift in innate and adaptive immune response in chinese immigrants living in a western environmentThere is a marked shift in innate and adaptive immune responses in Chinese immigrants after living in a Western environment for several years
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Early Life Ovalbumin Sensitization and Aerosol Challenge for the Induction of Allergic Airway Inflammation in a BALB/c Murine ModelThis protocol adapted an experimental animal model of disease for sensitization to ovalbumin during the immediate post-weaning period beginning at 21 days of age