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Research

Epigenome-wide association study reveals longitudinally stable DNA methylation differences in CD4+ T cells from children with IgE-mediated food allergy

Food allergy is mediated by a combination of genetic and environmental risk factors, potentially mediated by epigenetic mechanisms.

Research

Maternal and family factors and child eating pathology: Risk and protective relationships

This study aimed to identify maternal and family factors that may predict increases or decreases in child eating disorder symptoms over time, accounting for...

ORIGINS

The ORIGINS Team is studying early environments and parental physical health and genetics to uncover when and why non-communicable diseases (NCDs) develop.

Research

Effects of prenatal n-3 fatty acid supplementation on offspring resolvins at birth and 12 years of age: a double-blind, randomised controlled clinical trial

This study aimed to assess the effect of n-3 fatty acid supplementation in pregnancy on offspring SPM at birth and 12 years of age (12 years)

Research

Mums Minds Matter

Amy Jenny Susan Desiree Keerthi Finlay-Jones Downs Prescott Silva Kottampally BPsych(Hons), MPsych(Clinical), MHealthEcon, PhD (Clin Psych) BApplSci

Research

Egg-sensitised infants have elevated CD4+ effector memory T regulatory cells from birth

IgE-mediated sensitisation to egg is common in infants. In some cases, the processes leading to egg sensitisation are established in early life, even before introduction to solid foods. The underlying mechanisms remain poorly understood. 

Research

Effect of maternal prebiotic supplementation on human milk immunological composition: Insights from the SYMBA study

Immunomodulatory proteins in human milk (HM) can shape infant immune development. However, strategies to modulate their levels are currently unknown. This study investigated whether maternal prebiotic supplementation alters the levels of immunomodulatory proteins in HM. 

News & Events

Cow’s milk protein allergies on the rise in our kids

Up to three out of every 100 babies develop cow's milk protein allergy (CMPA) in their first year of life – and this number appears to be on the rise

Research

Can polymorphisms in the fatty acid desaturase (FADS) gene cluster alter the effects of fish oil supplementation on plasma and erythrocyte fatty acid profiles? An exploratory study

Overall results of this preliminary study suggest that supplementation with fish oil may only significantly increase DHA in minor allele carriers of FADS1 SNPs. Further research is required to confirm this novel finding.