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Research
Bringing optimised COVID-19 vaccine schedules to immunocompromised populations: statistical elements and designBringing optimised coronavirus disease 2019 (COVID-19) vaccine schedules to immunocompromised populations (BOOST-IC) is a multi-site, adaptive platform trial designed to assess the effect of different booster vaccination schedules in the Australian immunocompromised population on the immunogenicity, safety and cross-protection against COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its variants.
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Urinary tract infections in children: building a causal model-based decision support tool for diagnosis with domain knowledge and prospective dataDiagnosing urinary tract infections (UTIs) in children in the emergency department (ED) is challenging due to the variable clinical presentations and difficulties in obtaining a urine sample free from contamination.
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Predicting the causative pathogen among children with osteomyelitis using Bayesian networks – improving antibiotic selection in clinical practiceWe have demonstrated the potential use of Bayesian Networks in improving antibiotic selection for children with osteomyelitis
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Advancing the management and control of typhoid fever: a review of the historical role of human challenge studiesImproved understanding of Salmonella Typhi infection can help accelerate the development of improved vaccines and diagnostic tests necessary for disease control
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Reply to Farmakiotis et al:Typhoid fever in an inner city hospital: a 5-year retrospective review.This paper comments on the difficulty diagnosing typhoid and other infections causing severe diarrhoea, especially in regions where it is a common problem...
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Characterization and novel analyses of acute stress response patterns in a population-based cohort of young adults: influence of gender, smoking, and BMIIn a young adult cohort, stress-response patterns, in addition to other parameters vary with gender, smoking, and BMI
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The interaction between respiratory viruses and pathogenic bacteriaData on asymptomatic identification rates of respiratory viruses are limited, particularly in Indigenous populations, who suffer a high burden of OM.
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Impact of influenza on hospitalization rates in children with a range of chronic lung diseasesThis large population-based study suggests a significant healthcare burden associated with influenza in children with a range of chronic lung diseases
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Choosing primary endpoints for clinical trials of health care interventionsThis narrative review describes the evolution, range and relative strengths and weaknesses of endpoints used in late phase trials
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The contribution of viruses and bacteria to community-acquired pneumonia in vaccinated children: A case - Control studyRespiratory viruses, particularly respiratory syncytial virus and human metapneumovirus, are major contributors to pneumonia in Australian children