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Research

High burden of infectious disease and antibiotic use in early life in Australian Aboriginal communities

Early life infections drive high antibiotic prescribing rates in remote Aboriginal communities

Research

Does Child Care in the First Year of Life Pose a Risk for Concurrent and Future Ear Infections?

The longitudinal analyses found no evidence of increased (or decreased) long-term risk of ear infections in subsequent waves associated with attending a child care centre

Research

A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma

We present a curated panel of 12 readily-usable, cell lines representing the spectrum of molecular subtypes of IDH-wildtype glioblastoma

Research

The evolution of local food environments within established neighbourhoods and new developments in Perth, Western Australia

People living in new developments, and low SES areas of Perth, may be disadvantaged with poorer access to healthy food and greater exposure to unhealthy food outlets

Research

Concurrent developmental course of sleep problems and emotional/behavioral problems in childhood and adolescence as reflected by the dysregulation profile

Findings provide evidence for a strong association in the development of sleep problems and difficulties of dysregulation with emotion, cognition, and aggression

Research

Tricho-hepatic-enteric syndrome (THES) without intractable diarrhoea

We report an 8 year old girl who was diagnosed with THES by the Undiagnosed Disease Program-WA with compound heterozygous pathogenic variants in SKIV2L

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Evening and night work schedules and children's social and emotional well-being

The findings show that both mothers’ and fathers’ evening and night work schedules are linked to an increase in children's externalizing and internalizing behavior

Research

An integrative analysis of non-coding regulatory DNA variations associated with autism spectrum disorder

Overall, we found that the regulatory variants in autism spectrum disorder cases were enriched in ASD-risk genes and genes involved in fetal neurodevelopment

Research

Association of Genetic and Environmental Factors with Autism in a 5-Country Cohort

Based on population data from 5 countries, the heritability of ASD was estimated to be approximately 80%

Research

Birth seasonality and risk of autism spectrum disorder

In the first multinational study of birth seasonality of autism spectrum disorder, there was evidence supporting the presence of seasonal trends in Finland and Sweden