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A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1To identify new susceptibility loci for psoriasis, we undertook a genome-wide association study of 594,224 SNPs in 2,622 individuals with psoriasis...
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Changes in the FEV/FVC ratio during childhood and adolescence: an intercontinental studyIn children, the ratio of forced expiratory volume in 1 s (FEV₁) to forced vital capacity (FVC) is reportedly constant or falls linearly with age...
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Global strategy for the diagnosis and management of asthma in children 5 years and youngerAsthma is the most common chronic disease of childhood and the leading cause of childhood morbidity from chronic disease as measured by school absences...
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Randomised controlled trial analysing supplementation with 250 versus 500 units of vitamin D3, sun exposure and surrounding factors in breastfed infantsThe rate of non-compliance with vitamin D supplementation is as high as 45%. This is why randomised controlled trials are needed to analyse the response...
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The effectiveness of enhanced cognitive behavioural therapy for eating disorders: An open trialThe aim of this study was to examine the effectiveness of Enhanced Cognitive Behaviour Therapy (CBT-E) for eating disorders in an open trial for adults...
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Plasma versus serum levels of osteopontin and mesothelin in patients with malignant mesothelioma-Which is bestBlood-based markers for malignant mesothelioma (MM), particularly soluble mesothelin and osteopontin, are currently of great clinical interest.
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Identifying peroxidases and their oxidants in the early pathology of cystic fibrosisWe aimed to determine whether myeloperoxidase (MPO) is the main peroxidase present in the airways of children with cystic fibrosis (CF) and to assess which oxid
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Addison Disease – diagnosis and initial managementAdrenal insufficiency is a rare disease caused by either primary adrenal failure (Addison disease) or by impairment of the hypothalamic-pituitary-adrenal axis
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Prenatal stress and risk of behavioral morbidity from age 2 to 14 years:The maternal experience of stressful events during pregnancy has been associated with a number of adverse consequences for behavioral development offspring...
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Immune-modifying properties of topical vitamin D: Focus on dendritic cells and T cellsTopical creams containing the active form of vitamin D (1,25-dihydroxyvitamin D3; 1,25(OH)2D3) or analogues of this compound are currently used with some succes