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Research

Dual control of antitumor CD8 T cells through the programmed death-1/programmed death-ligand 1 pathway and immunosuppressive CD4 T cells

Tumors have evolved multiple mechanisms to evade immune destruction. One of these is expression of T cell inhibitory ligands such as programmed death...

Research

Risk factors for full- and partial-syndrome early adolescent eating disorders: a population-based pregnancy cohort study

To identify prospective predictors of eating disorders in a population-based sample of 14-year-old boys and girls, using previously collected antenatal...

Research

Altered attainment of developmental milestones influences the age of diagnosis of rett syndrome

This study describes the attainment of gross developmental milestones and regression, and assesses the relationships between genotype and age at diagnosis.

Research

TLR1/2 activation during Heterologous prime-boost vaccination (DNA-MVA) enhances CD8+ T cell responses providing

Leishmania (Viannia) parasites present particular challenges, as human and murine immune responses to infection are distinct from other Leishmania species

Research

Obstetric malpractice litigation and cerebral palsy in term infants

The aim of this paper is to review relevant research papers to aid practitioners involved in obstetric malpractice litigation.

Research

Slam and dc-sign measles receptor polymorphisms and their impact on antibody and cytokine responses to measles vaccine

Despite the use of measles vaccine, measles virus continues to circulate and cause severe disease

Research

Immediate and Longer Term Immunogenicity and Safety of a Single Dose of the Combined Haemophilus influenzae Type

Hib-primed but MenC-naive toddlers (N = 433) were randomized to receive 1 dose of Hib-MenC-TT or separate Hib-TT and MenC-CRM197 vaccines.

Research

Novel non-TCR chromosome translocations t(3;11)(q25;p13) and t(X;11)(q25;p13) activating LMO2

In T-cell acute lymphoblastic leukemia (T-ALL) cytogenetic alterations juxtapose the LIM-domain-only-2 gene (LMO2) with T-cell receptor loci.

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Population-based trends in pregnancy hypertension and pre-eclampsia: an international comparative study

The objective of this study was to compare international trends in pre-eclampsia rates and in overall pregnancy hypertension rates...

Research

Obstetric profiles of foreign-born women in Western Australia using data linkage, 1998-2006

Despite Western Australia (WA) having the highest proportion of overseas-born residents of any Australian state, no previous study has examined the general...