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Research

Sensitizing the Tumor Microenvironment to Immune Checkpoint Therapy

In this review we explore the current literature about the predictive characteristics of the tumor microenvironment and discuss therapeutic approaches

Research

The relationship between abdominal pain and emotional wellbeing in children and adolescents in the Raine Study

Abdominal pain in children and adolescents associates with depression, anxiety, being bullied, unhappiness and reduced overall health-rating during adolescence

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How many words are Australian children hearing in the first year of life?

These results show that a word gap related to maternal education is not apparent up to twelve months of age

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Clinical characteristics of Western Australian children diagnosed with type 2 diabetes before 10 years of age

We aimed to describe the characteristics of Western Australian children aged less than 10 years diagnosed with type 2 diabetes between June 2000 and June 2017

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Prevalence and outcomes of young people with concurrent autism spectrum disorder and first episode of psychosis

Individuals with concurrent first episode of psychosis and ASD can present with distinct clinical characteristics that require specialised assessment and treatment

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Innate Immune Responses and Gut Microbiomes Distinguish HIV-Exposed from HIV-Unexposed Children in a Population-Specific Manner

In both high- and low-income countries, HIV-negative children born to HIV-positive mothers (HIV exposed, uninfected [HEU]) are more susceptible to severe infection than HIV-unexposed, uninfected (HUU) children, with altered innate immunity hypothesized to be a cause. Both the gut microbiome and systemic innate immunity differ across biogeographically distinct settings, and the two are known to influence each other.

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Profile of severely growth-restricted births undelivered at 40 weeks in Western Australia

Higher levels of poor perinatal outcomes among FGR births highlight the importance of appropriate management including fetal growth monitoring

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Bilateral murine tumor models for characterizing the response to immune checkpoint blockade

This protocol describes bilateral murine tumor models that display a symmetrical yet dichotomous response to immune checkpoint blockade

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Reflections and perceptions of chronic tinnitus during childhood

Reflections and perceptions of chronic tinnitus during childhood

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A qualitative examination of the cognitive and behavioural challenges experienced by children with fetal alcohol spectrum disorder

The findings suggest consistency between caregivers in their reports of the difficulties experienced by children with Fetal Alcohol Spectrum Disorder