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Research

Harmonised collection of data in youth mental health: Towards large datasets

The use of this core set of data will facilitate the pooling of psychopathological and neurobiological data into large datasets

Research

Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology

Here, we identifyied 12 suggestively significant loci associated with intake of any macronutrient in 91,114 European ancestry participants

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Increased facial asymmetry in autism spectrum conditions is associated with symptom presentation

Significantly greater depth-wise facial asymmetry was identified in autistic children relative to the two comparison groups

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Immune-mediated ECM depletion improves tumour perfusion and payload delivery

We have devised a new approach to degrade tumour ECM, which improves uptake of circulating compounds

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Tumor necrosis factor α induces α1B-adrenergic receptor expression in keratinocytes

Our results suggest that inflammatory cytokines released during injury stimulate α1-AR expression in keratinocytes

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Lessons learned in the development of sustained release penicillin drug delivery systems for the prophylactic treatment of rheumatic heart disease (RHD)

The current prophylactic treatment to prevent rheumatic heart disease requires four-weekly intramuscular injection of a suspension of the poorly soluble benzathine salt form of penicillin G (BPG) often for more than 10 years. In seeking to reduce the frequency of administration to improve adherence, biodegradable polymer matrices have been investigated.

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Sleep disturbances in Rett syndrome: Impact and management including use of sleep hygiene practices

Attention to sleep hygiene remains an important management strategy for sleep problems in Rett syndrome

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The importance of the exposome and allostatic load in the planetary health paradigm

The concept of planetary health emphasizes that human health is intricately connected to the health of natural systems within the Earth's biosphere

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Discovery of Transcription Factors Novel to Mouse Cerebellar Granule Cell Development Through Laser-Capture Microdissection

This study provides an initial insight into the TFs of cerebellar granule cells that might be important for development