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Research

Changes in cell morphology guide identification of tubulin as the off-target for protein kinase inhibitors

Early changes in cell morphology upon treatments are a strong indication that the inhibitor is directly targeting tubulin

Research

A profile of social, separation and generalized anxiety disorders in an Australian nationally representative sample of children and adolescents

Social, separation and generalized anxiety disorders in young people are relatively common and impairing, with a high level of comorbidity

Research

Psychosocial resilience and vulnerability in Western Australian Aboriginal youth

We review findings from our previous studies which show the application of a person-based resilience framework of analysis in the context of WA aboriginal youth

Research

The glycaemic benefits of a very-low-carbohydrate ketogenic diet in adults with Type 1 diabetes mellitus may be opposed by increased hypoglycaemia risk and dyslipidaemia

This study provides the first evidence that, ketogenic diets in adults with Type 1 diabetes are associated with excellent HbA1c levels and little glycaemic variability

Research

The Ultra-High-Risk for psychosis groups: Evidence to maintain the status quo

Our findings demonstrate that Ultra-High-Risk groups evidence a similar clinical risk profile when we expand this beyond transition to psychosis

Research

Autism and psychosis: Clinical implications for depression and suicide

This study examines the association of autism spectrum traits, depressive symptoms and suicidal behaviour in individuals with psychotic experiences

Research

Incidental inequity

Reporting incidental genomic findings requires various considerations. One of these is that 'the clinical validity and utility of variants should be known'.

Research

A microbiome case-control study of recurrent acute otitis media identified potentially protective bacterial genera

We characterised the nasopharyngeal microbiome of these children in comparison to children with rAOM to identify potentially protective bacteria.